An observational learning task using Barnes maze in rats
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چکیده
منابع مشابه
Spatial Learning and Memory in Barnes Maze Test and Synaptic Potentiation in Schaffer Collateral-CA1 Synapses of Dorsal Hippocampus in Freely Moving Rats
Introduction: Synaptic plasticity has been suggested as the primary physiological mechanism underlying memory formation. Many experimental approaches have been used to investigate whether the mechanisms underlying long-term potentiation (LTP) are activated during learning. Nevertheless, little evidence states that hippocampal-dependent learning triggers synaptic plasticity. In this study, we in...
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MOTIVATION Spatial learning is one of the most widely studied cognitive domains in neuroscience. The Morris water maze and the Barnes maze are the most commonly used techniques to assess spatial learning and memory in rodents. Despite the fact that these tasks are well-validated paradigms for testing spatial learning abilities, manual categorization of performance into behavioral strategies is ...
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The Barnes maze is a spatial memory task that requires subjects to learn the position of a hole that can be used to escape the brightly lit, open surface of the maze. Two experiments assessed the relative importance of spatial (extra-maze) versus proximal visible cues in solving the maze. In Experiment 1, four groups of mice were trained either with or without a discrete visible cue marking the...
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Verapamil is a drug that blocks L-type calcium channels and selectively inhibits calcium ion entry into the central and peripheral nervous system cells. Verapamil is used acutely and chronically in treatment of some cardiovascular and central nervous system disorders. It has also been shown that acute administration of verapamil has no significant effect on learning and memory in rats, but the ...
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ژورنال
عنوان ژورنال: Cognitive Neurodynamics
سال: 2018
ISSN: 1871-4080,1871-4099
DOI: 10.1007/s11571-018-9493-1